I used to be a MALDI-TOFfer
My old job was shooting DNA fragments with a pretty serious UV laser so they'd ionize and fly down a meter-long aluminium tube and pass a timed detector. You never quite lose that thrill of sitting down at the control console and pulling the trigger on that thing, feeling the power of energy being released and seeing the spectrum generate every time it pulsed.
Actually the only sound it made was a faint clicking and the only visible effect was flashing light on the microscope camera screen. But to be honest the next-gen sequencing technology that replaced my spectrophotometer setup is much less fun to run.