It's not clear how fully accurate AlphaFold's predictions are.
Also the lack of knowledge how they change shape in the presence of others. Not saying what they have done is not bloody amazing because it is but I'm getting the impression around 200 million proteins need xray diffraction (with AI help) and then we need to mix those 200 million proteins with every other one to see how they interact. So there is a bit of work left to do.
Me - I'd then run it on the LUCA proteins to see if we can get back to LUCAs ancestors - I think it likely there were many proto-life forms and two or more merged to make LUCA that went and ate all the others or just left them no room to evolve.
Might be nice to have an AI on bio-security so we can ensure some of the stuff NATTtrash alludes to dont get out. It would obviously have to be a completely separate AI wtih no knowledge of Deep Blue etc to prevent it getting any ideas above its station which would need an AI to ensure complete information AI separation which obviously wouldnt work...
Let me drink about this some more..