In the Windows 10 roll-out for the NHS a couple of years ago, I was still encountering the odd bit of software that refused to work without elevation. (Some cardigraph monitoring thing comes to mind). Upper echelons in IT delared that we would not install such software on the new builds, and tough!
Just a couple of weeks ago I was experimenting with MS's keyboard layout designer. I couldn't get it to work, until a lightbulb went off, and I experientally ran it as Admin. Yep, that was the only way to get it to work.